Nomoro ea Cas: 146-56-5 Foromo ea molek'hule: C20H21ClN2O4
| Melting Point | 176-178°C |
| Botenya | 1.02 g/cm³ |
| mocheso oa polokelo | e tabohile mocheso oa kamore, ho tsoa letsatsing le sebakeng se mongobo |
| ho qhibiliha | 50 mg/ml(Ka ethanol);Ha e kenelle ka metsing |
| tshebetso ya mahlo | +111.6 likhato (C=1, methanol) |
| Ponahalo | phofo e tshweu kapa e batlang e le tshweu |
| Bohloeki | ≥97% |
ke "mohanyetsi oa calcium ea dihydropyridine" (mohanyetsi oa calcium, kapa blocker e liehang) e thibelang motsamao oa "calcium ion" ho ea liseleng tsa mesifa e boreleli le li-myocyte tsa pelo.Lintlha tsa liteko li fana ka maikutlo a hore li amahanngoa le "libaka tse tlamang" bakeng sa "dihydropyridines" le "non-dihydropyridines".Bobeli ba mesifa ea pelo le methapo ea methapo 'contractile process' e ipapisitse le ho kena ha "extracellular calcium ion" liseleng tsena ka likanale tse khethehileng tsa ion.ka mokhoa o ikhethileng e thibela ho phalla ha li-ion tsa khalsiamo ho pholletsa le lisele tsena tsa lisele, mochine o amang lisele tsa mesifa ea mesifa ho feta lisele tsa pelo.Phello e mpe ea inotropic (Inotrope), kapa ho fokotseha ha contractility ea myocardial, e ka bonoa in vitro.Leha ho le joalo, liphello tse joalo ha li e-s'o bonoe liphoofolong tse tsamaisoang ka har'a tekanyo e behiloeng ea phekolo.Serum calcium concentrations ha e amehe ke .Sebakeng sa pH sa 'mele, ke motsoako oa ionised (pKa = 8.6) oo tšebelisano le li-receptor tsa calcium channel li khetholloang ke lebelo le tsoelang pele la ho kopana ha sebaka sa receptor le ho arohana, 'me mokhoa ona o tsoelang pele oa sekhahla o fella ka phello e tsoelang pele ea ho qala.
ke peripheral arterial vasodilator e sebetsang ka kotloloho mesifa e boreleli ea methapo, e bakang phokotso ea peripheral vascular resistance le ho fokotseha ha khatello ea mali.Mokhoa o nepahetseng oa ho imolla angina ha o utloisisoe ka botlalo, empa ho nahanoa hore o kenyelletsa tse latelang: Angina ea boithaopo: Ho bakuli ba nang le angina e matla, NORVASC e fokotsa ho hanyetsa ka ho feletseng (afterload) nakong ea mosebetsi oa pelo boemong leha e le bofe ba boikoetliso le ho fokotsa sekhahla. sehlahisoa sa khatello, ka hona ho fokotsa tlhoko ea oksijene ea myocardial.
Qalong, 5mg hanngoe ka letsatsi, e eketseha ho fihla ho 10mg hang ka letsatsi.
