Nomoro ea Cas: 330784-47-9 Foromo ea molek'hule: C23H26ClN7O3

Tlhaloso e Khutšoanyane:

Nomoro ea Cas: 330784-47-9

Lebitso la lik'hemik'hale:

Mokhoa oa molek'hule: C23H26ClN7O3

Mantsoe a tšoanang:(S) -2-(2-Hydroxymethyl-1-pyrrolidinyl) -4-(3-chloro-4-methoxybenzylamino) -5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine

4 - [(3-Chloro-4-methoxybenzyl) amino] -2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl) -5-pyrimidinecarboxamide

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Tlhaloso ea Lihlahisoa

Melting Point	150-152°C
Botenya	1.372
mocheso oa polokelo	E tiisitsoe ka sehatsetsing, ka tlas'a -20°C
ho qhibiliha	DMSO (Hanyenyane), Methanol (Hanyenyane, e futhumetseng)
tshebetso ya mahlo	N/A
Ponahalo	Bosoeu ho isa ho bosoeu
Bohloeki	≥98%

pharmacodynamics

(Zepeed) e ile ea amoheloa ke Lefapha la Bophelo la Korea bakeng sa phekolo ea ho se sebetse ha erectile (ED) ka August 2011.ke mofuta o khethehileng oa 5 phosphodiesterase (PDE5) inhibitor.e tlalehoa e le eona e khethollang ka ho fetisisa PDE5 inhibitor 'marakeng.Ho qala ha Tmax le halofo ea bophelo le tsona lia fapana har'a li-inhibitors tsa PDE5 tse rekisoang.Sildenafil e na le T_maxka 1 h le halofo ea bophelo ba 3-5 h.Vardenafil e batla e tšoana le T_maxea 0.6 h le halofo ea bophelo ba 4-6 h.Tadalafil e na le halofo ea nako e telele ka ho fetisisa har'a lithethefatsi tse rekisoang ka halofo ea bophelo ba 17 h.e na le ts'ebetso e potlakileng e fihlang ho T_maxka 0.6 h le halofo ea bophelo ba 1.2 h.Kakaretso ea (TA-1790) e hlalositsoe libukeng tsa patent.Tsela e ka sehloohong ea ho felisa ke ka bile le mantle.e ile ea boela ea fumanoa e khutlisetsoa morao ka enterohepatic recirculation.