Nomoro ea Cas: 21187-98-4 Molecular Formula Featured Image

Nomoro ea Cas: 21187-98-4 Foromo ea Molek'hule

Tlhaloso e Khutšoanyane:

Nomoro ea Cas: 21187-98-4

Lebitso la lik'hemik'hale:

Mokhoa oa molek'hule: C15H21N3O3S

Mantsoe a tšoanang:BP;) -4-methyl-;1-(3-azabicyclo(3.3.0)oct-3-yl) -3-(p-tolylsulfonyl)urea;1-(hexahydrocyclopenta(c)pyrrol-2(1h )-yl)-3-(p-tolylsulfonyl)-ure;1-(hexahydrocyclopenta(c)pyrrol-2(1h)-yl)-3-(p-tolylsulfonyl)urea;benzenesulfonamide,n-(((hexahydrocyclopenta( c)pyrrol-2(1h)-yl)amino)carbonyl;n-(4-methylbenzenesulfonyl)-n'-(3-azabicyclo(3.3.0)oct-3-yl)urea;Tetrabenzyl Voglibose HCl

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Tlhaloso ea Lihlahisoa

Melting Point	163-169 °C
Botenya	1.2205 (khakanyo e fosahetseng)
mocheso oa polokelo	Sepakapaka se sa tsitsang, Mocheso oa Kamore 2-8°C
ho qhibiliha	methylene chloride: e qhibilihang
tshebetso ya mahlo	N/A
Ponahalo	Hantle-Bosoeu Tiileng
Bohloeki	≥98%

Tlhaloso

Ke moemeli oa molomo oa antihyperglycemic o sebelisetsoang ho phekola lefu la tsoekere la mofuta oa II.Ke ea sehlopha sa sulfonylurea sa secretagogues ea insulin, e susumetsang lisele tsa pancreatic β ho lokolla insulin.e tlama ho β cell sulfonyl urea receptor (SUR1), e tsoela pele ho thibela likanale tsa potasiamo tse hlokolosi tsa ATP.Ka hona, phokotso ea potasiamo e fokotseha haholo, e bakang depolarization ea lisele tsa β.Ebe liteishene tsa calcium tse itšetlehileng ka voltage ka seleng ea β lia buleha, e leng se bakang ts'ebetso ea calmodulin, e lebisang ho exocytosis ea insulin e nang le li-granules tsa secretion.Liphuputso tsa morao-rao li boetse li bontšitse hore li ka ntlafatsa boemo ba anti-oxidant le vasodilation ea nitric oxide-mediated ho Mofuta oa 2 oa lefu la tsoekere le ho sireletsa lisele tsa pancreatic beta ho senya ke hydrogen peroxide.

tšebeliso le litekanyetso

ke sethethefatsi sa hypoglycemic sa molomo se sebelisetsoang ho phekola lefu la tsoekere le sa itšetleheng ka insulin.Kalafo ea lefu la tsoekere e amanang le botenya kapa lefu la methapo, ho batho ba baholo ba nang le lefu la tsoekere la mofuta oa 2. Lefu la tsoekere ke boemo bo sa foleng (bo tšoarellang) bo amang tsela eo 'mele oa hau o fetohang ka eona. dijo hore e be matla.e fokotsa tsoekere ea mali ka ho susumetsa tlhahiso ea insulin ho tsoa liseleng tsa β tsa lihlekehleke tsa Langerhans.