Nomoro ea Cas: 171599-83-0 Foromo ea Molek'hule: C 2 2 H 3 0 N 6 O 4 S·C 6 H 8 O 7 = 666.70
| Melting Point | 49-53 ° |
| Botenya | 1.05 g/cm³ |
| mocheso oa polokelo | sebaka se phodileng, se omeletseng le ho qoba ho pepesehela kganya kapa mocheso o phahameng |
| ho qhibiliha | E qhibiliha ha bonolo ka har'a ethanol, acetone, ether, benzene le methylene chloride, empa e sa qhibilihe metsing. |
| tshebetso ya mahlo | [α]D20 = +61.0° (tharollo ea ethanol) |
| Ponahalo | phofo e tsoeu ho isa ho e mosehla o mosehla |
Nakong ea ts'usumetso ea thobalano, methapo ea parasympathetic, non adrenergic le non cholinergic nerve (NANC) e qetellang le lisele tsa vascular endothelial li lokolla nitric oxide (NO) tlas'a ketso ea nitric oxide synthase (NOS).Methapong ea mali, soluble guanylate cyclase (sGC) hangata e sebelisoa ke NO, mme sGC e sebetsa ho guanosine triphosphate ho hlahisa cGMP.CGMP ka corpus cavernosum ea penis e na le phello e matla ea vasodilator ka ho fokotsa khatello ea kelello ea Ca2 + liseleng tse boreleli tsa mesifa ea corpus cavernosum, e leng se bakang ho phomola ha lisele tsa mesifa e boreleli le ho eketseha ha mali ka har'a corpus cavernosum, e lebisang pele. ho erection.Jinyang alkali e fokotsa tekanyo ea ho senyeha ha cGMP, kahoo e boloka phello e khathollang ea cGMP ho corpus cavernosum ea penis le ho baka penile erection.Ka vivo, cGMP e nyenyefalitsoe ebile ha e sebetse ke PDE5.
E loketse ho phekola ho se sebetse ha erectile (ED) ea botona, e sebetsa hantle bakeng sa ho se sebetse ha erectile ho bakoang ke tšebeliso ea li-antidepressants, li-antipsychotics, le lithethefatsi tse thibelang khatello ea kelello, hammoho le ho se sebetse ha erectile ho bakoang ke ho buuoa kapa ho sithabela maikutlo.
E ka etsoa matlapa, lipilisi, li-capsules tse thata, li-capsules tse bonolo, 'me e ka sebelisoa e le veine ea moriana, mokelikeli oa molomo, kofi, li-granules, matlapa a chewable, lozenges, chewing gum, le mefuta e meng ea litekanyetso.Bakeng sa batho ba baholo, tekanyo e lokela ho ba 10-100mg ka letsatsi, e ka eketsoang kapa ea fokotseha ho ea ka boemo ba mosebedisi.Ho molemo ho e nka ka mpeng e se nang letho (haholo-holo qoba ho e nka ka lijo tse nang le mafura a mangata), 'me u se ke ua noa joala pele u sebelisa Tea (ho noa ha hoa lokela ho jeoa ka nako e le' ngoe, ho bolelang hore ho noa joala ka nako e le 'ngoe. nako e ka fokotsa haholo mosebetsi oa erectile oa Viagra).
Nako e sebetsang: Batho ba bangata ba e nka hora e le 'ngoe hore e sebetse.Ho kgothaletswa ho noa meriana hoo e ka bang hora ea 1 pele ho thobalano, ka liphello tsa eona tse tšoarellang lihora tse 48 ho isa ho tse 72, 'me tse ling li ka nka lihora tse 116.
