Nomoro ea Cas: 224785-91-5 Foromo ea Limolek'hule:C23H33ClN6O4S Setšoantšo se Featured

Nomoro ea Cas: 224785-91-5 Foromo ea molek'hule: C23H33ClN6O4S

Tlhaloso e Khutšoanyane:

Nomoro ea Cas: 224785-91-5

Lebitso la lik'hemik'hale:

Foromo ea molek'hule:Setšoantšo sa C23H33ClN6O4S

Mantsoe a tšoanang: HCL;Vardenafi;Nuviva;fafinafei;Valdenafil;Levitra, Valdenafil;USP/EP/BP;Levitra,Valdenafil.HCl;224785-91-5;

Re romelle lengolo-tsoibila

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Tlhaloso ea Lihlahisoa

Melting Point	214-216°C
Botenya	N/A
mocheso oa polokelo	Boemo ba leholimo bo sa tsitsang, 2-8°C
ho qhibiliha	N/A
tshebetso ya mahlo	N/A
Ponahalo	Cyrstalline e tšoeu ho ea ho e tšoeu
Bohloeki	≥98%

pharmacodynamics

e ne e le moemeli oa bobeli oa ho rekisoa 'me o ne a e-na le molemo oa hore nako ea eona ea ho qala ha ea ka ea fokotseha ka ho noa meriana ka mpeng e tletseng.Ke makhetlo a 30 a matla ho feta a inhibitor ea PDE5 (e bolelang IC50, 3.9 nM) ho feta sildenafil le linako tse 10 tse matla ho feta tadalafil, ka khetho e kholo (> linako tse 1,000) bakeng sa PDE5 ea batho ho feta PDE2, PDE3, le PDE4 ea batho le khetho e itekanetseng (> makhetlo a 80) bakeng sa PDE1.The PDE inhibitory selectivity le in vitro le in vivo potency ea PDE5 inhibitor e ncha.ka ho khetheha e thibetse hydrolysis ea cGMP ka PDE5, e nang le IC50 ea 0.7 nM (sildenafil 6.6 nM).IC50 ea bakeng sa PDE1 e ne e le 180 nM, bakeng sa PDE6 11 nM, le bakeng sa PDE2, PDE3 le PDE4 ho feta 1,000 nM.